Beyond Pass/Fail: Measuring the Degree of Dose Proportionality - 5/26/2026

By inverting the question asked in a widely cited 2000 paper, a new metric reveals that dose proportionality is better understood as a continuous property of a compound than as a binary regulatory verdict.

https://www.linkedin.com/posts/brian-smith-67891a5_drugdevelopment-biostatistics-clinicalpharmacology-ugcPost-7465038232687280128--7qq/?utm_source=share&utm_medium=member_desktop&rcm=ACoAAAEGlDwBwD0msjnYupwRjlV-PWIsMwwWd3w