A tale of two subgroups, one that failed and one that changed a label, revealing why logic, not just math, must drive subgroup thinking.

A call to rethink our regulatory interpretations, especially in early-phase research, and to refocus on patient impact, not just procedural perfection.

I still have trouble believing these events.

How a Quiet Violation of Statistical Logic Undermines Your Trial Outcomes

Learn why it’s best for quantitative disciplines to collaborate, not compete.

See how a sharp-fitting suit and a sharp-fitting model have more in common than you think.

Learn about the Lilly Clinic: a place that had impact.

Moving to a more "Macro" topic. See if this logic makes sense to you.

Once you agree that the model that has the higher likelihood is the better one. There is still an issue. Are the likelihoods truly different from each other? Find out how I think you can determine this.

There are a lot of times when one has two models that they wish to compare for their "predictive performance." Without careful contemplation as to the metric of comparison one may be left in the cold.

A peak at the origins of my fascination with analytical sciences.

Conventional wisdom tends to a singular approach of drug development. This article wonders if there can be situations where there is a better alternative to what is nearly always adopted. This thought is driven by clinical pharmacology understanding.

Better language for communicating results.

A thought about determining the sample size for a study

Find out the surprising reason why.

See how seemingly unrelated are related.

A Method for Ranking teams (Based on Statistics!)

A little perspective of a component necessary to be a great quantitative scientist.

Nothing like a little history in mathematics article. Enjoy.