Brian Smith Brian Smith

Likelihood is where it is at, Jack - 5/12/2025

There are a lot of times when one has two models that they wish to compare for their "predictive performance." Without careful contemplation as to the metric of comparison one may be left in the cold.

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Brian Smith Brian Smith

Adding A Tool to the Toolbox of Drug Development - 4/28/2025

Conventional wisdom tends to a singular approach of drug development. This article wonders if there can be situations where there is a better alternative to what is nearly always adopted. This thought is driven by clinical pharmacology understanding.

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